| abstract |
(57) [Summary] (Modified) [Purpose] To provide a novel piperazine derivative that inhibits the binding of fibrinogen to fibrinogen receptor and is useful for the treatment of thrombosis, epilepsy, myocardial infarction, inflammation, arteriosclerosis and tumor. To do. [Structure] For example, 3- (3- (4-amidinopiperazin-1-ylacetamido) benzamide) -propionic acid, methyl 4- (4- (4-guanidinobenzoyl) piperazin-1-yl) butyrate, N- ( 3- (4-amidino-2-oxopiperazin-1-ylacetamido) benzoyl) -L-alpartic acid dimethyl; piperazine derivatives represented by the following and salts thereof, a method for producing the same and the compound and / or physiologically A pharmaceutical composition comprising an acceptable salt thereof. |