abstract |
(57) [Summary] (Modified) [Structure] Suppressing calcium uptake by leukocytes containing the compound of general formula (I) or a pharmaceutically acceptable salt thereof, and the compound or a pharmaceutically acceptable salt thereof Drugs to do. [In the formula, Ar represents a phenyl group which may be substituted with a substituent such as halogen or C 1 -C 6 alkyl, a furyl group or a cenyl group; R 1 to R 3 are hydrogen, halogen and C 1 -C 6 alkyl, C 1 -C 6 alkoxy, benzyloxy, amino, etc.] [Effect] The compound of formula (I) suppresses the calcium uptake in leukocytes and platelets, and thereby causes immune diseases, inflammatory diseases and the like. It regulates the fibrinolytic response during the process of blood coagulation (thrombosis). |