| abstract |
(57) [Summary] [Objective] To provide an optical biosensor. The present invention relates to a biosensor obtained by coating a TiO 2 waveguide with a biological recognition molecule. The coating is composed of an organic carrier layer to which the acceptor molecules are attached, the carrier layer having the general formula I It is composed of molecules. This layer is a Si O 2 waveguide Coupling to the TiO 2 waveguide either directly via the atoms or, if desired, via an intermediate layer. Receptor molecules are biological molecules capable of recognition, such as antigens, antibodies, receptors, Ds DN. A, ssDNA. Receptor molecules are arranged two-dimensionally or three-dimensionally on the sensor surface, and the receptor molecules are immobilized non-directionally or directionally on the organic carrier layer. [Effect] It enables highly sensitive and highly specific quantification of a test substance molecule. |