| abstract |
(57) [Summary] [Object] To provide a cyclic imino derivative having beneficial pharmacological properties, for example, an inhibitory action on aggregation, a pharmaceutical composition containing these compounds, and a preparation method thereof. [Structure] 1- (4-amidinophenyl) -3- [4- (2-Carboxy-ethyl) -phenyl] -4-methoxy-3-pyrrolin-2-one, 1- (4-amidinophenyl) -3- [4- (2-carboxy-ethyl) -phenyl] -4- Morpholino-3-pyrrolin-2-one, 1 -(4-amidinophenyl) -3- [4- (2-carboxy-ethyl) -phenyl] -pyrrolidin-2-one, 1- (4-aminomethyl-phenyl) -3- [4- (2 -Carboxy-ethyl) -phenyl] -4-methoxy- 3-pyrrolin-2-one, 1- (4-amidinophenyl) -3- [4- (2-carboxy-ethyl) -phenyl] -3-methyl-pyrrolidin-2,4-dione and their analogs Cyclic imino derivatives including, tautomers thereof, stereoisomers including a mixture thereof, and salts thereof. |