abstract |
(57) [Summary] (Modified) [Objective] To provide a thioformamide derivative which is highly safe and easy to use, and is useful as an antihypertensive agent and a therapeutic agent for heart disease. 【Constitution】 {In the formula, [Wherein R 7 is a group such as a benzyloxy group, R 11 , R 12 is a group such as H, OH, a benzoyloxy group, a benzyloxy group, —NR 14 R 15 (R 14 , R 15 is a group such as H and a benzyl group)] Z is a group such as —CH 2 —, A Represents a group such as a (substituted) imidazolyl group or an imidazopyridyl group, and R 1 to R 4 represent groups such as H and a lower alkyl group. } The thioformamide derivative represented by these, or its pharmacologically acceptable salt. |