| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afd115dec46c157d3739020ebd4d866b |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55 |
| filingDate |
1992-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1471d337c8304b3879b7cf24a33d78ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_343d1701a10c15992253ce77eb3e2629
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e8a0b984e22810841941b9a60722580
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a0c7a45010f5d3ad9264a16625be488
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56de872510aed8cae8d9fd6c7defb1c5 |
| publicationDate |
1994-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H0625011-A |
| titleOfInvention |
Liquid preparation containing human urinary trypsin inhibitor and method for producing the same |
| abstract |
(57) [Summary] [Object] An object of the present invention is to provide a trypsin inhibitor-containing liquid preparation having excellent stability during storage and a method for producing the same. [Structure] The present invention is a human urinary trypsin inhibitor-containing liquid preparation having a low ionic strength and a pH of 7 or less. Production of the liquid preparation, which comprises heating a human urinary trypsin inhibitor-containing solution to 60 to 100 ° C. at pH 5 to 7 and then lowering the pH to 2 to 5 and performing heat treatment for 1 to 30 minutes while maintaining the temperature. Method. [Effect] The present invention can improve the stability of a trypsin inhibitor during long-term storage, and in particular, can prepare a preparation that suppresses the formation of a high molecular weight substance by polymerization and a low molecular weight substance by decomposition. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H07278015-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003514789-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9879246-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4988115-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003514790-A |
| priorityDate |
1992-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |