http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H06247941-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52a65b677bbedbe7bf090dd556a7cc43 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F230-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F226-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F20-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F26-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F30-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1992-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af44b5d552db83cdd3e339b46670d867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7446c4a1ebe6aa6163253864426c21f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fd0d1fa78e4bb70db168840297582fe |
| publicationDate | 1994-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H06247941-A |
| titleOfInvention | Polymer having 5-fluorouracil residue |
| abstract | (57) [Summary] [Purpose] To provide 5-fluorouracil sustained-release anticancer agents that are highly absorbable (water-soluble) and have low toxicity. [Structure] First, a polymerizable derivative of 5-fluorouracil represented by the following formula (1) is produced, and this is prepared using the general formula (3). (Wherein R is H or CH 3 , and X is a water-soluble group or a residue of a water-soluble molecule), and a copolymerizable monomer having a water-soluble group or hydrophilicity is copolymerized, The average molecular weight is represented by the general formula (2) (wherein R is H or CH 3 , X is a water-soluble group or a residue of a water-soluble molecule, and Y is 0.004 to 0.5). A polymer (2) having a 5-fluorouracil residue of 1 × 10 4 to 1 × 10 6 and a water-soluble group is obtained. The structure of the polymer (2) is as shown in the general formula (2), but the bonding direction of the monomer units is not necessarily limited to the direction described in the general formula (2), and each monomer The method of polymerizing the body units may be block or random. [Chemical 1] |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4563040-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005213153-A |
| priorityDate | 1992-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.