http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H06225785-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7c7159366be37ecf8a4c595cfa235a8 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-58 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate | 1993-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eaf3ba5d3de22c20fd50ed7a47a6875 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb8e643ce8bd58bf212801b06b003138 |
| publicationDate | 1994-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H06225785-A |
| titleOfInvention | Novel t-PA variant |
| abstract | (57) [Summary] The present invention relates to the amino acid sequence of Bat-PA corresponding to the part of the sequence around the double-stranded region in the amino acid sequence of natural t-PA. Of t-PA substituted with the partial sequence of. [Effect] The modified t-PA of the present invention has B Since it contains an amino acid sequence that retains fibrin specificity in at-PA, it is a novel t-PA variant with improved fibrin specificity in vivo, resulting in a systemic bleeding tendency t. -It is expected to be used as a therapeutic agent for thrombosis with reduced side effects of PA. |
| priorityDate | 1993-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 109.