| abstract |
(57) [Summary] (Modified) [Structure] A benzamide derivative represented by the general formula I, an optical antipode thereof, or a pharmacologically acceptable salt thereof. [Effect] The compound of the present invention has an excellent PAF antagonism, and is effective for all diseases caused by PAF (bronchial asthma, nephritis, shock, myocardial infarction, stroke, ulcer, DI). C, autoimmune disease, thrombosis, etc.) is effective for treatment and prevention. (B, D: hydrogen atom, etc., E: pyridyl group, etc., n: 0-2 Integer,) R 2: R 3 R 4 N- equal (R 3, R 4: may have a substituent group C 4 -C 12 Aryl groups, etc.) |