Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C331-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-38 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C331-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C313-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-27 |
filingDate |
1993-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_229806326422e934b992a4cdccf2d0b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5411594cdb3470baa8a6136d4426e1bb |
publicationDate |
1994-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H06211824-A |
titleOfInvention |
Ranitidine manufacturing method |
abstract |
(57) [Summary] (Modified) [Structure] N-methyl- of the following formula (II) characterized by comprising the following steps (1), (2) and (3): A method for producing ranitidine, which comprises the production of a 1-alkylthio-2-nitroethenamine derivative. (1) The following formula (I) Manufacturing the compound of. (2) A compound of the following formula (II) is prepared by reacting a compound of the following formula (I) with a suitable alkylating agent. To produce the N-methyl-1-alkylthio-2-nitroethenamine derivative of. (3) The derivative of the following formula (II) is prepared with 2- [5- (N, N- Reacting with dimethyl-aminomethyl) -2-furanmethylthio] ethylamine. [Effect] High safety and yield can be obtained. |
priorityDate |
1984-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |