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filingDate 1993-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_229806326422e934b992a4cdccf2d0b3
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publicationDate 1994-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H06211824-A
titleOfInvention Ranitidine manufacturing method
abstract (57) [Summary] (Modified) [Structure] N-methyl- of the following formula (II) characterized by comprising the following steps (1), (2) and (3): A method for producing ranitidine, which comprises the production of a 1-alkylthio-2-nitroethenamine derivative. (1) The following formula (I) Manufacturing the compound of. (2) A compound of the following formula (II) is prepared by reacting a compound of the following formula (I) with a suitable alkylating agent. To produce the N-methyl-1-alkylthio-2-nitroethenamine derivative of. (3) The derivative of the following formula (II) is prepared with 2- [5- (N, N- Reacting with dimethyl-aminomethyl) -2-furanmethylthio] ethylamine. [Effect] High safety and yield can be obtained.
priorityDate 1984-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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