abstract |
(57) [Summary] [Structure] A (thio) urea derivative represented by the formula (I) (wherein T is O and S; R 1 is alkyl; A is a benzene ring and a heterocycle; R 2 is H and alkyl). , Alkoxy, O H, halogen, COOR 5 (alkyl), CONR 8 R 9 (alkyl) and the like; R 3 is H, alkyl, alkenyl, COOR 11 alkyl, CONR 12 R 13 alkyl; Z is tetrazolyl; m is 1 to 3) or a salt thereof. [Chemical 1] [Effect] It has angiotensin II antagonism and is useful for prevention and / or treatment of hypertension and the like. |