| abstract |
(57) [Summary] (Modified) [Structure] Including a benzimidazole represented by the general formula (I), a 1-, 3-isomer mixture thereof and a salt thereof, a method for producing the same, and the compound or a salt thereof Pharmaceutical composition. [In the formula, R a is C 1-3 -alkyl, R b is R 1 NH- (this hydrogen atom may be substituted with an R-CX- group or the like), and R c is C 2-4- alkyl. , R d represents carboxy or tetrazolyl, R 1 is a hydrogen atom or a C 1-3 -alkyl group, and R is a C 1-5 -alkyl group, C 1-3 -alkoxy group, dialkylamino group or the like. Yes, X is NO 2 -C H =, (CH 3) 2 C =, CN-N =, CH 3 SO 2 - N = etc. [Effect] These novel compounds are particularly effective as angiotensin antagonists. |