| abstract |
(57) [Summary] [Structure] The following formula (I): {In the formula, A, B and E are each a group = CH- or = N-. With the proviso that at least one of A, B or E is = N- R is a C 3 -C 6 cycloalkyl group, C 2 -C 6 alkenyl group or C 2 -C 6 alkynyl group, R 1 represents H or a C 1 -C 3 alkyl group, and R 2 and R 3 are H, halogen, NO 2 , CN, C 1 -C, respectively. 6 alkyl, C 3 to C 6 cycloalkyl, C 1 to C 6 alkoxy, C 1 to C 6 alkylthio, —CO—R 4 (R 4 = H, C 1 -C 6 alkyl or C 3 -C 6 cycloalkyl) or C 1 -C 4 haloalkyl, haloalkoxy or haloalkylthio group, or R 2 and R And 3 together represent a group —O—CH 2 —O—} and a base addition salt thereof. Effects The compounds according to the invention have a pronounced anti-inflammatory activity. |