Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e05ecc55c1afdb18fa200bbf0bb4c642 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-746 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-773 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-788 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-847 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-049 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6929 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6923 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 |
filingDate |
1993-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_921dcb5282714fedc57cfa20c9063f05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92a15f7c143cb9e157d1ffbdbefa43ca |
publicationDate |
1994-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-H06211646-A |
titleOfInvention |
Composition containing nanoparticles and method for producing the same |
abstract |
(57) [Summary] [Object] To provide a therapeutic or diagnostic composition having a controlled cloud point and a method for producing the same. The composition comprises nanoparticles in which a nonionic surfactant is adsorbed on the surface as a surface modifier, and charged phospholipids are contained in combination as a cloud point modifier. The cloud point modifier is present in the composition in an amount sufficient to raise the cloud point of the surface modifier. Preferred nonionic surfactant surface modifiers are poloxamine or tyloxapol, and preferred charged phospholipid cloud point modifiers include dimyristoylphosphatidylglycerol. Further disclosed is a method for producing the nanoparticles, comprising the step of contacting the nanoparticles with a cloud point modifier for a time and under conditions sufficient to raise the cloud point of the surface modifier. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2015525741-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8957199-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5600299-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004520443-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2000516244-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009524665-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2010061880-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010061880-A1 |
priorityDate |
1992-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |