| abstract |
(57) [Summary] (Modified) [Structure] A 4-aminoquinazoline derivative of formula (I) and a salt thereof, a method for producing the same, and a cGMP phosphodiesterase inhibitor and a TXA 2 synthase inhibitor containing the compound as an active ingredient. For example ) [Effect] The compound of formula (I) is useful as a therapeutic agent for hypertension, myocardial infarction, asthma, and other diseases caused by increased cGMP metabolism, and as an anti-inflammatory agent or antithrombotic agent by inhibiting TXA 2 biosynthesis. Is. |