| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed28726de9f916f355f8adc331e736b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-65 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-65 |
| filingDate |
1993-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a645a4e6923bbca7b4040009671d3af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc84305f149e8d8f95902f265f9d1c6b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d4d7ffdd878aa4c572d86569bb475b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22ccb78b9023939f980466eed0a774e0 |
| publicationDate |
1994-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H06192103-A |
| titleOfInvention |
Compositions containing non-steroidal anti-inflammatory agents and virtually non-antibiotic tetracyclines |
| abstract |
(57) [Summary] [Objective] A method for reducing a bone defect in a mammal caused by a tissue-destructive condition associated with excessive metalloproteinase activity and a therapeutic method capable of avoiding the side effect of antibiotic tetracycline therapy. To provide. A method of reducing mammalian bone defects due to a tissue-destructive condition associated with excessive metalloproteinase activity, which exhibits effective anti-metalloproteinase properties, but which effectively exhibits antibiotic properties. An amount of a non-steroidal anti-inflammatory agent that significantly reduces tissue destruction and / or bone loss when used in combination with an amount of tetracycline not shown and an amount of tetracycline that effectively exhibits anti-metalloproteinase properties. Is administered to the mammal. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2002508327-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4733266-B2 |
| priorityDate |
1992-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |