| abstract |
(57) [Summary] (Modified) [Structure] Aspergillomarasmin A [Formula (1)], Aspergillomarasmin B [Formula (2)], physiologically acceptable salts thereof, or a mixture thereof. And an aspergillomarasmin A, an aspergillomarasmin B, a physiologically acceptable salt thereof, or a mixture thereof as an active ingredient. Agent. HOOC-CH 2 -CH (COOH) -NH-CH 2 -CH (COOH) -NH-CH 2 -CH (NH 2) -C OOH (1) HOOC-CH 2 -CH (COOH) -NH-CH 2 -CH (COOH) -NH-CH 2 -COOH (2) [Effect] It is highly safe and has a high endothelin converting enzyme inhibitory activity. |