| abstract |
(57) [Summary] (Modified) [Structure] In producing an optically active compound from (RS) -α-methylbenzylamine by a diastereomer method using optically active mandelic acid as a resolving agent, the reaction system is Screw (α -Methylbenzyl) amine is added, and a salt of an inorganic acid or an organic acid of ammonia or a primary amine, And / or water-soluble inorganic salts are present. [Effect] The crystals of the sparingly soluble diastereomeric salt to be precipitated are obtained in the form of good filterability, so that a product having a high optical purity can be easily produced. |