| abstract |
(57) [Summary] [Structure] General formula: A substituted heterocyclic compound (where X = -O-, -S-,- SO- or -SO 2 -), the preparation and pharmaceutical compositions containing them. [Effect] This compound is a tamkinin receptor antagonist effective for the treatment of inflammatory diseases, pain or migraine and asthma, and a calcium channel blocker effective for the treatment of cardiovascular abnormalities such as angina, hypertension and ischemia. Is. |