| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1013 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-103
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
1992-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bedd921c2b89c5f3919bc4ea558e4c2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c16aaef2834bb69aa4b1fbb3f10e9e2d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0e777b8bfe39c1123dd065e403ddce7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fd1904f9bca4043d31557a3e2c88fc4 |
| publicationDate |
1994-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H06157589-A |
| titleOfInvention |
Farnesyl-protein transferase non-substrate inhibitors |
| abstract |
(57) [Summary] (Modified) [Constitution] Amino acid sequence Cys-Xaa 1 -Xaa 2 -Xaa 3 [wherein Cys is a cysteine amino acid, Xaa 1 may be any amino acid, and Xaa 2 is phenylalanine or p-fluorophenylalanine Xaa 3 can be any amino acid] and acts as a non-substrate inhibitor to inhibit farnesyl-protein transferase and block the transformation of normal cells into cancer cells. [Effect] This compound inhibits farnesyl-protein transferase (FTase) and farnesylation of oncogene, and is effective in treating cancer. |
| priorityDate |
1991-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |