| abstract |
(57) [Summary] (Modified) [Constitution] General formula (I) [In the formula, X and Y are each independently hydrogen or -C H 2 CH 2 R, where n is 4 and both X and Y are not hydrogen or a piperidinoethyl group. Here, R is a pyridyl group or a substituted amino group (NR 1 R 2 ). Wherein R 1 is hydrogen or a lower alkyl group, and R 2 is a 2- (3-indolyl) ethyl group or an aralkyl group, or R 1 and R 2 together with the nitrogen atom to which they are attached. Nitrogen-containing 5- or 6-membered heterocycle, nitrogen-containing- An oxygen heterocycle, or these heterocycles form a ring fused with benzene). n is an integer of 4 to 8] and an addition salt thereof with a pharmacologically acceptable acid. [Effect] This compound exhibits an excellent gastric acid secretion inhibitory action and has no side effect, and is therefore useful as an anti-ulcer drug. |