abstract |
(57) [Summary] [Object] To provide an artificial novel polypeptide corresponding to human collagen type V, which is useful as an insulin-binding carrier. [Structure] General formula (X) m- (Y) n- (Z) (where X is a cell adhesion domain peptide of human fibronectin, Y is a spacer, and Z is represented by SEQ ID NO: 1 in the sequence listing) A polypeptide containing an amino acid sequence An artificial functional polypeptide represented by m and n is 1 or 0). Z is the polypeptide in the α1 chain of human collagen type V with Hyps at positions 6, 9, and 33 replaced by Pro. [Effect] It is useful as a new polypeptide in the field of utilizing insulin. |