| abstract |
(57) [Summary] (Modified) [Structure] Expression [Wherein R 1 is H, F, CF 3 , —COOR a (R a = H, alkyl), - S (O) m R 3 (R 3 = H, alkyl, aryl; m = 0,1,2), - NR 4 R 5 (R 4, R 5 = H, alkyl, aryl, aralkyl), - OR 6 (R 6 = H, alkyl, aryl, aralkyl, alkyl -SO 2 -, aryl -SO 2 -, Aralkyl -SO 2 -, CF 3, etc.); R 2 is F, C N, CF 3, CF 3 O , R b O (R b = alkyl, phenyl, benzyl); - NR 4 R 5 ( R 4, R 5 = above); x is a number of 1, 2, 3; y is Represents the number 0, 1] Of benzenesulfonamide alkyl] cycloalkano [1,2-b] indole and its preparation by condensation of phenylhydrazine with cycloalkane-benzenesulfonamide. [Effect] This compound is converted to a novel compound having a platelet aggregation inhibitory action by 2-carboxyethylation of indole-N. |