| abstract |
(57) [Summary] [Object] To provide a novel compound having excellent antitumor activity and immunostimulatory activity and its use. [Structure] A glycosphingolipid represented by the following formula (I). [Chemical 1] Here, when R 1 is α-D-galactopyranosyl and R 2 is the following group (a), R 3 is the following group (b) or (c), and R 1 is When β-D-glucopyranosyl and R 3 is the group (d) below, R 2 is the following group (a) or (e). (A) - (CH 2) 21 -CH 3 (b) -CH (OH) - (CH 2) 11 -CH (CH 3) 2 (c) -CH (OH) - (CH 2) 11 -CH (CH 3) -CH 2 -CH 3 (d) -CH = CH- (CH 2) 2 -CH = C- (CH 3) CH = CH- (CH 2 ) 6 -CH 3 (e) - (CH 2) it was harvested 22 -CH 3 Porifera Agerasu Mauri tee Ass subjected to extraction with an organic solvent, the extract A method for producing a glycosphingolipid, which comprises collecting the glycosphingolipid described above from a product. The compound of the present invention can be wholly synthesized by a chemical synthesis means combining various general chemical reactions relating to glycosphingolipids. An antitumor agent and an immunostimulant containing one or more of the above glycosphingolipids as an active ingredient. |