abstract |
(57) [Summary] (Corrected) [Structure] General formula: [Wherein R 1 is —COOH or —SO 3 H, one of R 2 and R 3 is a hydrogen group, the other is a hydroxyl group, a lower alkyloxy group, a lower alkylthio group, an amino group or a substituted amino group, and n is 3 ~ An integer of 5, A is the following formula: (R 4 is a hydrogen group, a lower alkyl group, a lower alkyloxy group, a trifluoromethyl group, a halogen group, or a nitro group) or a naphthyl group]. [Effect] It has a specific and competitive receptor antagonistic action of thromboxane A 2 and prostaglandin endoperoxide, and is useful as a non-prostanoid antagonist. |