| abstract |
(57) [Summary] [Purpose] To improve the penetration of anti-bacterial agents through the nail. In a dermatologic composition, at least one anti-bacterial agent selected from the group of allylamines, such as terbinafine hydrochloride and naphthifine hydrochloride, and in particular glycol, glycol monoether, glycol diether, dimethyl sulfoxide and caprolactam. , Dimethylisosorbide, isopropylidene glycerol, dimethylimidazolidinone, ethyl butyrate and polyoxyethylenated C A water-alcohol solvent in which at least one hydrophilic penetrating agent selected from 8- C 10 glyceride, polyethylene glycol 20 glyceryl laurate and dimethylacetamide, an anti-bacterial agent, and at least a part of the penetrating agent can be mixed. The medium is dissolved and contained. |