| abstract |
(57) [Summary] (Corrected) [Constitution] Dehydrocholate was added to methanol and ethanol. By hydrogenation in the presence of a platinum-based catalyst in a water-containing solvent consisting of hydrogen chloride, normal propanol, isopropanol, or a mixture thereof. α, 7α-Dihydroxy-12-oxocholanic acid is produced. [Effect] According to this production method, 3α, 7α-dihydroxy-12-oxocholanic acid can be produced from cholic acid in a smaller number of steps and with higher selectivity than in the conventional method involving selective acylation. |