abstract |
(57) [Summary] (Modified) [Objective] A carboxylic acid having superior therapeutic biological activity to the central nervous system or peripheral nervous system in vivo than the carboxylic acid itself is combined with a nitrogen-containing lipid. And a method for producing the same. [Structure] An organic amide of the general formula (1), a salt thereof, and a production method. [R 1 -CO is an acyl group of a known carboxylic acid having a potential or apparent therapeutic biological activity to the central nervous system or peripheral nervous system in vitro (provided that it binds to the nitrogen of a natural phospholipid or sphingolipid). Natural fatty acids and esters, benzoic acids and esters, and trimethoxybenzoic acid and esters, excluding prostaglandins, from the hydroxyl-substituted natural fatty acids described above, R 2 is a hydrogen atom, C 1-7 alkyl group or C 4-7 cycloalkyl group, R 3 N represents the residue of a phospholipid or a sphingolipid nitrogen-containing lipid] |