abstract |
(57) [Summary] [Structure] (In the formula, A is an optionally substituted cyclic hydrocarbon having 6 carbon atoms, m is an integer of 0 to 2, and n is an integer of 1 to 3, R 1 and R 2 are the same or different and each represents a hydrogen atom or a lower alkyl group. ) (N-bicyclic substitution) Aminomethylene bisphosphonic acid derivatives and pharmaceutically acceptable salts thereof. [Effect] The compound of the present invention has an anti-inflammatory action, an anti-rheumatic action and the like in addition to the bone resorption inhibiting action and is useful as a pharmaceutical. |