abstract |
(57) [Summary] [Object] To provide a tricyclic compound having an ACAT inhibitory action and useful as a therapeutic agent for hypercholesterolemia and a therapeutic agent for arteriosclerosis. [Structure] Formula (I) (Wherein, X 1 -X 2 is, CH = CH-CH = CH , CH = CH-CH = N or S-CH = CH, LM Represents C = CR 7, CH-CR 8 R 9 or CH-NR 10, Y-Z is, CH 2 -O, CH 2 -S , represents a CH = CH or CH 2 -CH 2, R 1 , R 2 , R 3 , R 4 , R 5 , R < 6 >, R < 7 >, R < 8> , R < 9 > and R < 10 > represent hydrogen, lower alkyl, etc.) or a pharmaceutically acceptable salt thereof. |