| abstract |
(57) [Summary] (Modified) [Structure] Biologically active peptides of primary formulas (I) to (III) isolated from the venom sacs of Protonectarina sylveirae .. (I) (II) (Xaa is a C-terminal amino acid, which is Leu in which the carboxyl group is amidated.) (III) (At the position of 7 ... 21, disulfide'-bond [Effect] The above-mentioned bioactive peptide has a strong action on histamine secretion from mast cells, and can be used, for example, for the development of a research reagent for allergy and inflammation involving mast cells, and a therapeutic agent therefor. |