http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H05317065-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f5033fcf56d5a13743728cc85a8dc3f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-004 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-00 |
filingDate | 1992-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abbb4f512e1b3c968bfdd37b3aa724c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee0c3941c9a57c344058ce0a479d2236 |
publicationDate | 1993-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H05317065-A |
titleOfInvention | Process for producing optically active cyanohydrins |
abstract | (57) Abstract: Aldehydes in a two-phase solvent system consisting of a homogeneous aqueous solution of the enzyme in the presence of hydroxynitrile lyase and a suitable organic solvent that is at least substantially immiscible with water. A process for the preparation of an optically active cyanohydrin by the addition of hydrogen cyanide to a carbonyl compound selected from and ketones, the homogeneous aqueous solution having a buffer concentration of between 0.005-0.1 mol per liter. Buffering with an acetate buffer or a non-acetate buffer, an organic phase: aqueous phase volume ratio of between about 5: 1 and about 1: 5, and the organic solvent of hydrogen cyanide and the carbonyl compound. A method of mixing the solution in a moderate amount with a homogeneous aqueous solution of hydroxynitrile lyase during the reaction period. [Effect] It is possible to perform the conversion with a relatively small amount of the enzyme in a relatively short amount of solvent and in a relatively short reaction time. It has sufficient enzyme recyclability, and thus produces optically active cyanohydrins with relatively low enzyme consumption, relatively high optical purity and yield, and easy processing. be able to. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7045322-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2295592-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H11349546-A |
priorityDate | 1991-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.