| abstract |
(57) [Summary] [Structure] 7-chloro-1,3-dihydro-5-phenyl-1- [N- (2,2,6,6- Spin-label compounds having a 1,4-diazepine skeleton such as tetramethylpiperidin-1-oxyl-4-yl) carbamoylmethyl] -2H-1,4-benzodiazepin-2-one. [Chemical 1] (In the formula, Me means a methyl group.) [Effect] The compound of the present invention has a sufficient half-life, crosses the blood-brain barrier, and selectively binds to the benzodiazepine receptor. It is useful as a probe for electron spin resonance (ESR) imaging of benzodiazepine receptor distribution. |