| abstract |
(57) [Summary] [Structure] General formula (1) (In the formula, R 1 , R 2 , R 3 and R 4 are each hydrogen, a lower alkyl group, a lower alkenyl group, a hydroxymethyl group, It represents a hydroxy group, a carboxymethyl group, a nitro group, a methoxy group, a sulfonylamino group or halogen. R 5 represents a carboxy group or a tetrazole group. ) And a therapeutic agent for hypertension and congestive heart failure containing the same. [Effect] The novel pyridine derivative of the present invention has angiotensin II receptor antagonistic activity and is useful as a therapeutic agent for hypertension and congestive heart failure or an intraocular pressure lowering agent. |