| abstract |
(57) [Summary] [Structure] General formula: In the formula, R represents a phenyl group substituted with nitro or chloro, R 1 and R 3 each represent a lower alkyl group, and R 1 2 represents a hydrogen atom, X represents a group of the formula COO 6 , wherein R 6 is a carbon optionally substituted by alkoxy, fluoro or N-benzyl-N-methylamino having 1 to 3 carbon atoms. Represents an achiral alkyl group of the number 1 to 4, R 4 represents an achiral alkyl group having 1 to 4 carbon atoms, which is different from R 6, and is a method for producing an optical antipode of a chiral 1,4-dihydropyridinedicarboxylic acid ester represented by [Effect] The above compound is useful as a drug for circulatory organs. |