abstract |
(57) Summary [Objective] To provide a composition that provides an in-situ biodegradable or bioerodible substrate. The substrate is used to release a bioactive substance and / or Used in animals to selectively increase growth cells and tissue regeneration. A composition suitable for forming a solid implant in-situ in vivo, comprising a biodegradable, bioerodible thermoplastic polymer that is substantially insoluble in water or body fluids. Consisting of a liquid and water or an organic solvent that is miscible or dispersed in the body fluid, the composition being capable of solidifying or solidifying upon contact with the water or the body fluid to form a solid microporous matrix, The substrate also has a central portion surrounded by the epidermis. |