| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c2b9dc89cc4ba060cc73bbf0c90bbb78 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6462
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-3153
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21007 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-72 |
| filingDate |
1992-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13d4cd6f0cde8f43444e0265f5a04947 |
| publicationDate |
1993-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H05304957-A |
| titleOfInvention |
Enzyme derivatives, their production method and pharmaceutical compositions containing them |
| abstract |
(57) [Summary] [Structure] The catalytic site essential for fibrin dissolution activity is pH In vivo blocked by groups that can be removed by hydrolysis at a rate such that the pseudo-first-order hydrolysis rate constant at 37 ° C in an isotonic aqueous medium of 7.4 is 10 -10 to 10 -3 / sec. A derivative or isolated derivative of fibrinolytic enzyme. [Effect] This enzyme derivative is effective in treating venous thrombosis. |
| priorityDate |
1978-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |