| abstract |
(57) [Summary] (Modified) [Objective] To provide a retroviral protease inhibitor useful as a therapeutic agent for retroviral diseases. [Structure] Formula (I) [R 1 and R 2 are bonds, amino acid residues; Y N is H, an amino-protecting group; Y C is OH or a carboxyl-protecting group; X is —CO—, —CH (OH) A compound of the formula (I) comprising culturing a bacterium belonging to the genus Kitasatosporia, collecting the obtained compound, and subjecting it to further Edman degradation, amino acid addition, acylation reaction, etc. And a therapeutic agent for a retroviral disease containing the compound. |