| abstract |
(57) [Summary] (Modified) [Structure] The following formula [I] Het-CH 2 X [I] (wherein Het represents an optionally substituted heterocycle, and X represents a leaving group). A compound represented by the following formula [II] Het-CH 2 NHCHO [II] (wherein Het represents a group having the same meaning as described above) by reacting a compound represented by The salt is obtained. The obtained formula [I By hydrolyzing the compound of I] or a salt thereof, a compound represented by the following formula [III] Het-CH 2 NH 2 [III] (wherein Het has the same meaning as defined above) is obtained. .. [Effect] Under mild conditions, the final target compound, a heterocyclic-substituted methylamine, can be obtained with a good yield and a good reaction rate. |