| abstract |
(57) [Summary] [Objective] To provide a novel functional polypeptide having both cell adhesion activity and cancer metastasis inhibitory activity. [Structure] General formula (Formula 1): A- (B) m- (C) n (In the formula, A is a polypeptide represented by SEQ ID NO: 1 in the sequence listing, B is a polypeptide represented by SEQ ID NO: 2 in the sequence listing, C is a polypeptide represented by SEQ ID NO: 3 in the sequence listing). , M, n are numbers of 1 or 0. However, the sum of m and n is 1 Which is the above). It is produced by binding a polypeptide derived from fibronectin. Expression by E. coli was also confirmed. [Effect] In addition to the cancer metastasis-suppressing action, it contributes to the repair of wound tissue and the maintenance of homeostasis. |