| abstract |
(57) [Summary] [Purpose] To easily obtain a drug product with a simple composition that can control the drug dissolution. [Structure] In a preparation in which a drug having different solubility depending on pH and porous cellulose are mixed, the solubility of the drug is controlled by supporting an acid or a base on the porous cellulose. In the preparation, the porous cellulose may carry a drug and an acid or a base, or may be provided with a film containing the drug and an acid or a base. A pharmaceutical composition in which an acid or a base is supported on porous cellulose is useful for controlling the drug dissolution property. The formulation may include additives such as binders. The preparation can be used as a solid preparation such as powder, granules, tablets and capsules. |