| abstract |
(57) [Summary] (Modified) [Structure] Expression A benzodiazepine analog represented by or a pharmaceutically acceptable salt thereof. Specifically, for example, (R) -N- (2, 3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl) -N ′ -(3-Methylphenyl) -urea. [Effect] An antagonist of gastrin and cholecystokinin (CCK) with increased aqueous solubility, treatment of panic disorder, anxiety disorder, oncological disorder, treatment of pain or induction of analgesia or treatment of drug or alcohol or It is useful in treating withdrawal responses caused by abuse. |