abstract |
(57) [Summary] [Objective] A synthetic intermediate of an optically active antibacterial compound useful as a drug can be easily obtained. [Configuration] Formula 1 (In the formula, X 1 and X 2 each independently represent a halogen atom or a hydrogen atom, Y represents an oxygen atom, a sulfur atom, methylene, or a hydrogen atom or a nitrogen atom which may have a substituent 1, R represents an alkyl group having 1 to 6 carbon atoms) is hydrogenated in the presence of an iridium-optically active phosphine complex and a halogen-containing salt to give a compound represented by the formula 2 Stereoisomers of compounds of formula (wherein X 1 , X 2 , Y and R are as defined above) are selectively prepared. |