abstract |
(57) [Summary] [Structure] General formula [Chemical formula 12] [R 1 : optionally substituted pyridyl; R 2 : H, C 1- C 4 alkyl, optionally substituted pyridyl; R 3: H, C 1 -C 4 alkyl; R 4: the formula: 13] (R 5 : H, C 1 -C 4 alkyl; R 6 , R 7 : optionally substituted phenyl, C 3 -C 6 cycloalkyl, A group having 5 to 6-membered cyclic heteroaryl); A: formula (R 8, R 9: H , C 1 -C 4 alkyl; D: C 2 -C 5 alkylene; a group having n: 2, 3); B: C 2 -C [4 alkylene] -containing thiazolidine amides and pharmaceutically acceptable salts thereof. [Effect] This compound has excellent anti-allergic action, anti-asthma action and platelet activating factor antagonist action, and is useful as an anti-allergic agent. |