| abstract |
(57) [Summary] (Modified) [Objective] To provide an inexpensive and physiologically harmless sulfoalkylating agent. [Constitution] 3-hydroxypropanesulfonic acid, 1,3- Propane sultone, 4-hydroxybutane-2-sulphonic acid and a hydroxyalkane sulphonic acid selected from the group consisting of 3-methyl-1,3-propane sultone or the corresponding alkanesultone derived from and internal control 13 C-NMR changes (ppm, with respect to TMS = 0) measured in D 2 O with dioxane as (1) 25.2, 27.8, 48.8, 61.1 and 69.5 or (2) A sulfoalkylating agent which is 15.4, 31.7, 34.4, 53.6, 60.0 and 68.5. |