abstract |
(57) [Summary] (Modified) [Objective] To provide a synthetic intermediate of 1α, 25-dihydroxy (-22E (or Z) -dehydro) -24-homovitamin D 3 derivative. [Structure] 1α, 3β, 25- represented by the general formula shown Trihydroxy-24-homocholesta-5,22-diene compound. This compound is 1α, 25-dihydroxy-2 It is used as a synthetic intermediate for 4-homovitamin D 3 derivatives. (In the formula, R is selected from the group consisting of hydrogen, an acyl group having 1 to about 4 carbon atoms, a benzoyl group, and a methoxymethyl group.) |