| abstract |
(57) [Summary] [Objective] Novel α-amino acid having NMDA antagonist activity, and NM containing the same as an active ingredient Provide a DA antagonist. [Structure] General formula (1): [In the formula, R 1 is —COOR 6 (provided that R 6 is a hydrogen atom, an alkyl group, an aryl group, or an aralkyl group), —CON (R 7 ) 2 (however, R 7 is the same as R 6 ). Or —PO (OR 6 ) 2 and R 2 , R 3 , R 4 and R 5, it is like the same as R 6, R 4 and R 5 may form a carbonyl group together with the carbon atom to which they are bonded, Q and A are alkylene groups which may have a substituent, and Y is —PO (OR 8 ). (OR 9 ) and the like]. General formula (2): [The symbols in the formula are the same as those in formula (1)] The α-amino acid represented by |