| abstract |
(57) [Summary] [Object] To provide a 5-membered heterocyclic compound having beneficial pharmacological properties, for example, an aggregation-inhibiting effect. [Structure] 1- [6- (4-amidino-phenyl) -3- Pyridazinyl] -4- (2-carboxy-ethyl) -imidazole, 5- (4-amidino-phenyl) -2- [4- (2-Carboxy-ethyl) -phenyl] -tetrazole, 4- (4-amidino-phenyl) -2- [4 -(2-Carboxy-ethyl) -phenyl] -thiazole, 3- (4-amidino-phenyl) -5- [4- (2 -Carboxy-ethyl) -phenyl] -1,2,4-triazole, 2- (4-amidino-4'-biphenylyl) -5- (2-carboxy-ethyl) -1,3,4- Thiadiazole, 1- [6- (4-amidino-phenyl) -3-pyridazinyl] -3- (2-carboxy-ethyl) -indole and 5-membered heterocyclic compounds consisting of analogs thereof, tautomers thereof, Stereoisomers and their salts, including mixtures thereof. |