| abstract |
(57) [Summary] (Modified) [Purpose] N-phenylthiourea derivatives and their pharmaceutical use. [Structure] In the treatment of atherosclerosis, the compound of general formula I, optionally in free or salt form Use of compounds with these substitutions. Also, a pharmaceutical composition comprising a compound selected from the above subgroup, and a subgroup of those compounds. A specific example of this compound is N- (5-chloro-2-methylphenyl) -N'-propylthiourea. These compounds may be prepared, for example, by reacting an isothiocyanate with an amine or converting urea to thiourea. |