| abstract |
(57) [Summary] [Structure] General formula: embedded image R 1 NH—CH (R 2 ) —CONH—A—ONO 2 (I) [wherein R 1 : H, C 1 -C 7 alkanoyl group , C 1 -C 6 alkoxycarbonyl group, C 6 -C 10 ants - ylcarbonyl group, C 7 -C 13 aralkyl group, C 7 -C 13 aralkyloxycarbonyl group, 5-6 membered aromatic heterocyclic carbonyl group; R 2 : C 1 -C 6 having a substituent Alkyl group; A: C 2 -C 5 amino acid derivatives and a pharmacologically acceptable salt thereof having an alkylene group. [Effect] This compound has excellent collateral vasodilatory action and antianginal action, and is useful as a therapeutic drug for angina. |